Victoria Police western region division two Detective Senior Sergeant Chris Asenjo said the man was arrested in Werribee on Friday morning without incident.

He said Hamilton criminal investigation unit detectives were attending and the man would be interviewed today.

"We can confirm police are not looking for any other person related to this incident," he said.

Detective Senior Sergeant Asenjo said the man was initially taken to hospital with concerns for his welfare.

"He was checked over and subsequently released back into police custody and is assisting with inquiries," he said.

It comes after a 60-hour manhunt following an incident at Hamilton's Kenna Avenue on Tuesday.

Police allege the man confronted a woman aged in her 40s inside the property at 1.10pm before assaulting her and threatening her with a knife.

He then fled the property in a Toyota HiLux which was found dumped nearly 80 kilometres away in Portland on Thursday.

Detective Senior Sergeant Asenjo thanked the community for information provided throughout the investigation.

"The community has been very helpful and we would like to thank them for their ongoing support," he said.

"We will continue to assist and support the victim."

More to come.

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