Nirranda and South Rovers took injuries away from their thrilling round one encounter at Walter Oval on Saturday.
Blues coach Brayden Harkness was "over the moon" with the 11.12 (78) to 8.6 (54) Warrnambool and District league victory.
He said the only downside was Jack Primmer sustained a hamstring injury.
Lions mentor Adam Matheson said Harry Boyd, who had kicked four goals up to midway through the second quarter, displaced his knee cap.
Matheson hopes he can have a quick recovery.
The Lions mentor added Sandy Williams should be available this week after getting scans for a facial injury.
While Primmer is in doubt, Harkness will have more players at his disposal this Saturday when the Blues face Allansford.
Nirranda went into their round one clash undermanned and came up against a young and fast Lions' outfit.
Luke Weel, Nick Couch, Jack Spokes, Dylan Willsher and Bronte McCann were unavailable.
Meanwhile, Harkness (knee), John Paulin (hamstring), Daniel Threlfall and Martin Angus (ankle) missed through injury.
Harkness said the Blues wanted to make sure their injured players were right and wouldn't rush them back.
He was pleased with the win given the amount of senior players and on-field leaders missing.
"The guys who did play really stood up and really led on the field," he said.
The Lions roared out the gates, kicking four goals straight in the opening term.
The Blues fought back and the game was right in the balance until the final minutes.
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