The 37-year-old has pleaded not guilty to murdering her partner Marcus Adams at the Port Fairy Catalina Caravan Park in September 2019.

Jurors retired to consider their verdict shortly before 1pm Tuesday.

The verdict will bring to a close a 10-day trial which started on November 25 and heard from multiple witnesses including residents who lived at the caravan park on the night of the fatal stabbing, as well as forensic investigators and medical experts.

Earlier, Monday: An accused murderer was lying when she recounted what happened inside a caravan at Port Fairy in the moments before a fatal stabbing, a jury has been told.

Jessica Wilson, 37, has pleaded not guilty in a Supreme Court trial to murdering her partner Marcus Adams at Port Fairy Catalina Caravan Park in 2019.

In closing addresses on Monday, senior crown prosecutor Nanette Rogers said Ms Wilson told at least six accounts of what happened in the lead up to Mr Adams' death and the jury could not be satisfied that they were truthful or accurate.

Ms Rogers said Ms Wilson first told a 000 operator that Mr Adams had fallen on the knife, which she said was "complete nonsense".

She said the accused had then told police the victim had a hammer, he grabbed her by the throat and that she was acting in self-defence.

Ms Rogers said significant details were missing, that the accounts were contradictory and that Ms Wilson was lacking in credibility.

She alleged that between the 000 call and police arriving, the accused saw a hammer in the caravan and "decided to volunteer its involvement in the circumstances".

She said there were more lies heard in a call between Ms Wilson and her mother six weeks after the fatal incident and that the accused was failing to keep her story together.

Ms Rogers said the crown case was put in two ways - the accused woman stabbed Mr Adams to the back with a 20 centimetre-long knife blade and in doing so, intended to kill or cause really serious injury, or that a minor assault occurred and that Ms Wilson "unnecessarily" defended herself.

She said the court heard evidence of minor injuries to the accused woman's neck and that Ms Wilson could have inflicted the injuries to herself, or that they could have been sustained if a minor scuffle occurred in the caravan.

Andrew Waters, representing Ms Wilson, said it was "grossly unfair" to criticise the accused woman for not mentioning the hammer and being grabbed by the throat during the first 000 call.

He said the woman was calling for help and would have given the shortest possible version of events rather than a detailed account of her self-defence case.

He said jurors heard evidence of Ms Wilson's potential infidelity and that on the night of the stabbing the man had steroids and a high level of MDMA in his system - drugs known to lead to aggression.

Mr Waters said it was the defence case that the accused was threatened with a hammer and grabbed around the neck during an altercation with the victim, who she then stabbed to the back in self-defence.

The jury is expected to begin deliberations on Tuesday.

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