Jessica Wilson, 37, has pleaded not guilty in Warrnambool Supreme Court to the murder of her partner Marcus Adams, 44, at Port Fairy's Catalina Caravan Park in 2019.

On Friday, jurors were played the audio of two 000 calls made by Ms Wilson after the stabbing occurred in the early hours of September 20.

It is not disputed that Mr Adams died of a fatal stab wound inflicted by the accused woman but lawyers for Ms Wilson said she acted in self-defence.

In the first call, a hysterical Ms Wilson could be heard telling an operator there was a "domestic" and that she was protecting herself.

She said her partner was breathing but unresponsive and bleeding.

Ms Wilson could be heard yelling: "Babe! Babe!"

In a second call, Ms Wilson was crying, she said she was scared and that she couldn't feel the victim's pulse.

She was directed to give CPR to the victim, which she did until an ambulance arrived.

Jurors also heard audio of a phone call made by Ms Wilson to her mother from prison on November 7, 2019.

During that call, Ms Wilson said the victim had his hand around her throat and they were arguing.

She said he wouldn't let her go so she grabbed a knife.

"I was defending myself, Mum, it's not like I just went out of my way to do that," she said.

"I tried to save him, Mum, it was f****."

The court heard it was the first call the accused woman had made to her mother since being in custody.

The mother and daughter were heard talking about drugs being found inside the caravan after the fatal incident.

Ms Wilson, who was in hospital for about four weeks prior to the fatal stabbing following a serious car crash, said she hadn't been home for months and that the victim had "been ordering shit off the dark web".

"This is what I came home to... I couldn't believe it," she was heard to say.

A homicide detective told the court a small spoon containing crystal methamphetamine was found in the caravan but it was not seized or forensically analysed.

Closing statements in the trial are expected to be heard early next week.

Now just one tap with our new app: Digital subscribers now have the convenience of faster news, right at your fingertips with The Standard: