Terang, Noorat, Mortlake and Peterborough residents will be voting for different MPs in the next state election under new boundary changes.
Lowan, held by Nationals' Emma Kealy and based around Horsham, will spread further south.
South West Coast, held by Liberal MP Roma Britnell, will spread east and Polwarth, held by Liberal MP Richard Riordan, will be reduced in size.
Mortlake will move to Lowan from Polwarth while Terang, Noorat and Peterborough will be transferred to South West Coast.
Portland, which had previously been earmarked for change, will remain in South West Coast.
Victoria's Electoral Boundaries Commission released the new state electoral boundaries to come into operation at the next state election in November 2022.
The EBC report, tabled in parliament on Thursday, includes the boundaries of each state district and region, and an explanation of how and why each change was made.
The EBC took account of the 127 written and 25 verbal submissions received from the Victorian community when preparing the final boundaries, which led to several key changes from the proposed boundaries.
Electoral Commissioner Warwick Gately, one of three members of the EBC, was pleased with the level of engagement in the process.
"Redivisions are a key part of Victoria's electoral system, as they ensure fair representation and an equal voice for all voters in state elections," he said.
The EBC released proposed boundaries on June 30 and invited public comment.
Mr Gately said after considering the written suggestions and objections and holding two public hearings, the EBC amended the proposed boundaries in 38 areas, transferring 127,425 electors to different electoral districts.
Comparing the existing boundaries with the new boundaries released today, a total of 910,384 electors (21.28 per cent of all electors) have been transferred to different districts.
The redivision has also replaced nine existing districts with nine new ones.
The boundaries released today are final and cannot be changed by parliament.
The existing boundaries will apply until next year's state election
This means that for more than one million electors, the electorate they vote in will change, even though they have not changed address.
The Victorian Electoral Commission (VEC) will run a statewide advertising program prior to the state election to raise awareness of the election and voters will be reminded that electoral boundaries have changed and that the electorate they vote in may have changed, even though their address has not.
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