Thousands took to the road for the start of the Great Victorian Bike Ride on Saturday, braving rain and gusty winds on a ride from Portland to Cape Bridgewater and back.

Despite grim conditions cyclists were in high spirits, managing smiles as they pushed through the 53-kilometre course.

A lunch stop at Portland Airport was largely washed out, with some riders choosing to miss a beachside rest break altogether and head back to town.

Joining the crowds for a second year were Brisbane couple Erin and Bruce Willmott, who brought along a special carriage for their young son.

Two-year-old Samuel was the ride's youngest entrant in 2008 and already loves the open road.

"Ever since we've been here he's been saying, 'Bike ride! Bike ride!'" Mrs Willmott said.

Tim McNally, who has been the Koroit Football Netball Club secretary for the past 17 years, is being joined by his son, Matt, for his first attempt at the ride.

"We just thought it was something we could enjoy doing together while raising a little bit of money for Diabetes Australia," he said.

Despite a dicky knee, Mr McNally said he was more worried about the impact of the bike seat on his rear end during the nine-day trek.

"I'm sure I'll be looking forward to the finish next Sunday. There are about 5000 riders, 500 volunteers and 300 contractors. It's a big show,'' he said.

"We're pretty well prepared. Matt and I did 1000km in training during the lead-up and up to 70km a day so we should be all right," he said.

This year's event is the 17th for George Marney, a West Footscray resident whose efforts help raise money for charities including the Royal Flying Doctor Service.

"It's great to see so many kids and school groups out here," the 73-year-old said.

"They're our future and our future cyclists.

"It gets them away from television and video games.

"It's all about the friendship and the camaraderie."